2000 - 2002              
Assistenzarzt am Evangelischen Krankenhaus Oldenburg,
Hand- und Plastische Chirurgie

 

2002 - 2005

Assistenzarzt an der BG-Unfallklinik Tübingen, Universitätsklinik für Plastische,
Hand- und Rekonstruktive Chirurgie mit Verbrennungschirurgie,
Eberhard-Karls-Universität Tübingen

 

2006 - 2007
Assistenzarzt im Behandlungszentrum Vogtareuth,
Brustzentrum der Klinik für Plastische Chirurgie

 

2007 - 2009
Oberarzt, Universitätsklinik für Plastische, Hand- und Rekonstuktive Chirurgie
mit Verbrennungschirurgie,
Eberhard-Karls-Universität Tübingen

 

2009

Erlangung der Lehrbefugnis - Venia Legendi an der Universitätsklinik für Plastische,
Hand- und Rekonstruktive Chirurgie mit Verbrennungschirurgie,
Eberhard-Karls-Universität Tübingen

 

2009 - 2011
Leitender Oberarzt, Plastische Chirurgie am Martin-Luther-Krankenhaus Berlin

 

2010

Erlangung der Zusatzbezeichnung Handchirurg

 

2011

Ernennung zum außerplanmäßigen Professor, Universitätsklinik für Plastische,
Hand- und Rekonstruktive Chirurgie mit Verbrennungschirurgie, 
Eberhard-Karls-Universität Tübingen

 

2012
Gründung der Abteilung Plastische und Ästhetische Chirurgie
Clinic Dahlem

 

2012 - 2014
Chefarzt und Begründer der Klinik für Plastische, Hand- und Rekonstruktive
Mikrochirurgie am St.-Marien-Krankenhaus Berlin

 

2015
Ärztlicher Direktor in der Privatklinik für Plastische und Ästhetische Chirurgie,
Clinic Dahlem

 

2016 - heute
Gründung der Sinis Klinik Berlin GmbH
Ärztlicher Direktor

 

 

Spezielle Qualifikationen

 

 

 

Mitgliedschaften

 

 

 

Sprachen

 

Deutsch

Englisch

Griechisch

Spanisch

Latein

 

 

Publikationen

 

Kraus A, Täger J, Kohler K, Haerle M, Werdin F, Schaller HE, Sinis N. Non-viral genetic transfection of rat Schwann cells with FuGENE HD© lipofection and AMAXA© nucleofection is feasible but impairs cell viability. Neuron Glia Biol. 2011 Jun 7:1-6.

Bendella H, Pavlov SP, Grosheva M, Irintchev A, Angelova SK, Merkel D, Sinis N, Kaidoglou K, Skouras E, Dunlop SA, Angelov DN. Non-invasive stimulation of the vibrissal pad improves recovery of whisking function after simultaneous lesion of the facial and infraorbital nerves in rats. Exp Brain Res. 2011 Jul;212(1):65-79.

Sinis N, Kraus A, Drakotos D, Doser M, Schlosshauer B, Müller HW, Skouras E, Bruck JC, Werdin F. Bioartificial reconstruction of peripheral nerves using the rat median nerve model. Ann Anat. 2011 Jul;193(4):341-6. Epub 2011 Mar 22. Review.

Sinis N, Manoli T, Schiefer JL, Werdin F, Jaminet P, Kraus A, Fornaro M, Raimondo S, Geuna S, Schaller HE. Application of 2 different hemostatic procedures during microsurgical median nerve reconstruction in the rat does not hinder axonal regeneration. Neurosurgery. 2011 May;68(5):1399-403; discussion 1403-4.

Radtke C, Sinis N, Sauter M, Jahn S, Kraushaar U, Guenther E, Rodemann HP, Rennekampff HO. TRPV channel expression in human skin and possible role in thermally induced cell death. J Burn Care Res. 2011 Jan-Feb;32(1):150-9.

Sinis N, Boettcher M, Kraus A, Werdin F, Schaller HE. Four-digit replantation in a mentally retarded person: a case report. Eplasty. 2010 Sep 30;10:e62.

Jaminet P, Kraus A, Manoli T, Werdin F, Schaller HE, Sinis N. Accidental median nerve injury during trapezium resection and ligament reconstruction for primary rhizarthrosis. Microsurgery. 2010 Sep;30(6):502-4.

Jaminet P, Werdin F, Jabsen JS, Kraus A, Sinis N, Schaller HE. [Limited portal carpal tunnel release. An alternative to classic open release?]. Orthopade. 2010 Nov;39(11):1029-35. German.

Gustin SM, Schwarz A, Birbaumer N, Sines N, Schmidt AC, Veit R, Larbig W, Flor H, Lotze M. NMDA-receptor antagonist and morphine decrease CRPS- pain and cerebral pain representation. Pain. 2010 Oct;151(1):69-76. Epub 2010 Jul 13.

Patrick J, Frank W, Theodora M, Armin K, Hans-Eberhard S, Nektarios S. The pedicled serratus anterior muscle wrap-around flap: A treatment option in the management of posttraumatic axillary neuroma and neuropathic pain. Ann Plast Surg. 2010 Aug;65(2):170-3.

Werdin F, Jaminet P, Rennekampff HO, Sinis N, Nusche A, Schaller HE.
[Does additive spongiosaplasty improve outcome after surgical therapy for solitary enchondroma in the hand?]. Handchir Mikrochir Plast Chir. 2010 Oct;42(5):299-302.

 

Söhnchen J, Grosheva M, Kiryakova S, Hübbers CU, Sinis N, Skouras E, Ankerne J,
Kaidoglou K, Fries JW, Irintchev A, Dunlop SA, Angelov DN.

Recovery of whisking function after manual stimulation of denervated vibrissal muscles requires brain-derived neurotrophic factor and its receptor tyrosine kinase B.
Neuroscience. 2010 Sep 29;170(1):372-80.

 

Stahl S, Lotter O, Stahl AS, Schaller HE, Sinis N. Immediate reconstruction of complex hand trauma with iliac crest bone graft and 2 pedicled fasciocutaneous skin flaps: a case report. Eplasty. 2010 Mar 10;10:e21.

 

Werdin F, Sinis N, Stetter C, Mittelbronn M, Schaller HE, Hering R. Poikilodermia, anhidrosis, hairless body, neurogenic muscle atrophy, and recurrent hematuria: a new syndrome? Clin Dysmorphol. 2010 Apr;19(2):65-8.

Manoli T, Jaminet P, Kraus A, Schaller HE, Werdin F, Sinis N. One-stage ear reconstruction after avulsion injury, using the amputated cartilage and a retroauricular transposition flap. Eplasty. 2010 Jan 18;10

Jaminet P, Werdin F, Kraus A, Pfau M, Schaller HE, Becker S, Sinis N. Extreme microstomia in an 8-month-old infant: bilateral commissuroplasty using rhomboid buccal mucosa flaps. Eplasty. 2009 Dec 26;10

Kiryakova S, Söhnchen J, Grosheva M, Schuetz U, Marinova T, Dzhupanova R, Sinis N, Hübbers CU, Skouras E, Ankerne J, Fries JW, Irintchev A, Dunlop SA, Angelov DN. Recovery of whisking function promoted by manual stimulation of the vibrissal muscles after facial nerve injury requires insulin-like growth factor 1 (IGF-1). Exp Neurol. 2010 Apr;222(2):226-234. Epub 2010 Jan 11

Sinis N, Di Scipio F, Schönle P, Werdin F, Kraus A, Koopmanns G, Masanneck C, Hermanns S, Danker T, Guenther E, Haerle M, Schaller HE, Geuna S, Mueller HW. Local administration of DFO-loaded lipid particles improves recovery after end-to-end reconstruction of rat median nerve. Restor Neurol Neurosci. 2009;27(6):651-62

Sinis N, Kraus A, Tselis N, Haerle M, Werdin F, Schaller HE. Functional recovery after implantation of artificial nerve grafts in the rat- a systematic review. J Brachial Plex Peripher Nerve Inj. 2009 Oct 25;4:19

Kraus A, Täger J, Kohler K, Manoli T, Haerle M, Werdin F, Hoffmann J, Schaller HE, Sinis N. Efficacy of various durations of in vitro predegeneration on the cell count and purity of rat Schwann-cell cultures. J Neurotrauma. 2010 Jan;27(1):197-203

Sinis N, Kraus A, Werdin F, Manoli T, Jaminet P, Haerle M, Schaller HE. [Nerve reconstruction and nerve grafting]. Chirurg. 2009 Sep;80(9):875-81; quiz 882

Sinis N, Manoli T, Werdin F, Kraus A, Schaller HE, Guntinas-Lichius O, Grosheva M, Irintchev A, Skouras E, Dunlop S, Angelov DN. Chapter 23: Manual stimulation of target muscles has different impact on functional recovery after injury of pure motor or mixed nerves. Int Rev Neurobiol. 2009;87:417-32.

Koopmans G, Hasse B, Sinis N. Chapter 19: The role of collagen in peripheral nerve repair. Int Rev Neurobiol. 2009;87:363-79

Sinis N, Kraus A, Papagiannoulis N, Werdin F, Schittenhelm J, Meyermann R, Haerle M, Geuna S, Schaller HE. Concepts and developments in peripheral nerve surgery. Clin Neuropathol. 2009 Jul-Aug;28(4):247-62.

Kraus A, Sinis N, Werdin F, Schaller HE. [Is intraoperative luxation of the ulnar nerve a criterion for transposition?] Chirurg. 2010 Feb;81(2):143-7. German.

Skouras E, Merkel D, Grosheva M, Angelova SK, Schiffer G, Thelen U, Kaidoglou K, Sinis N, Igelmund P, Dunlop SA, Pavlov S, Irintchev A, Angelov DN. Manual stimulation, but not acute electrical stimulation prior to reconstructive surgery, improves functional recovery after facial nerve injury in rats. Restor Neurol Neurosci. 2009;27(3):237-51.

Werdin F, Grüssinger H, Jaminet P, Kraus A, Manoli T, Danker T, Guenther E, Haerlec M, Schaller HE, Sinis N. An improved electrophysiological method to study peripheral nerve regeneration in rats. J Neurosci Methods. 2009 Aug 30;182(1):71-7. Epub 2009 Jun 6.

Sinis N, Horn F, Genchev B, Skouras E, Merkel D, Angelova SK, Kaidoglou K, Michael J, Pavlov S, Igelmund P, Schaller HE, Irintchev A, Dunlop SA, Angelov DN. Electrical stimulation of paralyzed vibrissal muscles reduces endplate reinnervation and does not promote motor recovery after facial nerve repair in rats. Ann Anat. 2009 Oct;191(4):356-70. Epub 2009 May 13.

Sinis N, Boettcher M, Werdin F, Kraus A, Schaller HE. Restoration of shoulder abduction function by direct muscular neurotization with the phrenic nerve fascicles and nerve grafts: a case report. Microsurgery. 2009;29(7):552-5.

Sinis N, Lanaras TI, Kraus A, Werdin F, Schaller HE, Peek A. Free latissimus dorsi flap with long venous grafts for closure of a soft tissue defect of the spine in a patient with Noonan's syndrome: A case report. Microsurgery. 2009 Mar 18. [Epub ahead of print]

Lanaras TI, Schaller HE, Sinis N. Brachial plexus lesions: 10 years of experience in a center for microsurgery in Germany. Microsurgery. 2009;29(2):87-94.

Bischoff A, Grosheva M, Irintchev A, Skouras E, Kaidoglou K, Michael J, AngelovaSK, Kuerten S, Sinis N, Dunlop SA, Angelov DN. Manual stimulation of the orbicularis oculi muscle improves eyelid closure after facial nerve injury in adult rats. Muscle Nerve. 2009 Feb;39(2):197-205.

Becker ST, Wiltfang J, Klapper W, Repp R, Sinis N, Warnke PH. Massive swelling of
the cervical region: an uncommon manifestation of B cell chronic lymphocytic leukemia. Oral Maxillofac Surg. 2008 Aug 8. [Epub ahead of print]

 

Evgenieva E, Schweigert P, Guntinas-Lichius O, Pavlov S, Grosheva M, Angelova S, Streppel M, Irintchev A, Skouras E, Kuerten S, Sinis N, Dunlop S, Radeva V, Angelov DN. Manual Stimulation of the Suprahyoid-Sublingual Region Diminishes Polynnervation of the Motor Endplates and Improves Recovery of Function After Hypoglossal Nerve Injury in Rats. Neurorehabil Neural Repair. 2008 Jul 8. [Epub ahead of print]

Werdin F, Sinis N, Schaller HE, Coerper S. [Recurrence rates of venous leg ulcers and the special importance of its surgical treatment]. Handchir Mikrochir Plast Chir. 2008 Apr;40(2):94-9. German.

Pavlov SP, Grosheva M, Streppel M, Guntinas-Lichius O, Irintchev A, Skouras E, Angelova
SK, Kuerten S, Sinis N, Dunlop SA, Angelov DN. Manually-stimulated recovery of motor function after facial nerve injury requires intact sensory input.
Exp Neurol. 2008 May;211(1):292-300. Epub 2008 Mar 5.

Sinis N, Schaller HE, Schulte-Eversum C, Lanaras T, Schlosshauer B, Doser M, Dietz K, Rösner H, Müller HW, Haerle M. Comparative neuro tissue engineering using different nerve guide implants. Acta Neurochir Suppl. 2007;100:61-4.

Grosheva M, Guntinas-Lichius O, Angelova SK, Kuerten S, Alvanou A, Streppel M, Skouras E, Sinis N, Pavlov S, Angelov DN. Local stabilization of microtubule assembly improves recovery of facial nerve function after repair. Exp Neurol. 2007 Sep 26;

Sinis N, Guntinas-Lichius O, Irintchev A, Skouras E, Kuerten S, Pavlov SP, Schaller HE, Dunlop SA, Angelov DN.. Manual stimulation of forearm muscles does not improve recovery of motor function after injury to a mixed peripheral nerve. Exp Brain Res. 2007 Oct 23.

Sinis N, Schaller HE, Becker ST, Schlosshauer B, Doser M, Roesner H, Oberhoffner S, Müller HW, Haerle M. Long nerve gaps limit the regenerative potential of bioartificial nerve conduits filled with Schwann cells. Restor Neurol Neurosci. 2007;25(2):131-41.

Guntinas-Lichius O, Hundeshagen G, Paling T, Streppel M, Grosheva M, Irintchev A, Skouras E, Alvanou A, Angelova SK, Kuerten S, Sinis N, Dunlop SA, Angelov DN. Manual stimulation of facial muscles improves functional recovery after hypoglossal-facial anastomosis and interpositional nerve grafting of the facial nerve in adult rats.
Neurobiol Dis. 2007 Oct;28(1):101-12. Epub 2007 Aug 14.

Sinis N, Birbaumer N, Gustin S, Schwarz A, Bredanger S, Becker ST, Unertl K, Schaller HE, Haerle M. Memantine treatment of complex regional pain syndrome: A preliminary report. Clin J Pain. 2007 Mar-Apr;23(3):237-43.

Sinis N, Haerle M, Becker ST, Schulte-Eversum C, Vonthein R, Rösner H, Schaller HE. Neuroma formation in a rat median nerve model – influence of distal stump and muscular coating. Plast Reconstr Surg. 2007 Mar;119(3):960-6.

Angelov DN, Ceynowa M, Guntinas-Lichius O, Streppel M, Grosheva M, Kiryakova SI, Skouras E, Maegele M, Irintchev A, Neiss WF, Sinis N, Alvanou A, Dunlop SA. Mechanical stimulation of paralyzed vibrissal muscles following facial nerve injury in adult rat promotes full recovery of whisking. Neurobiol Dis. 2007 Apr;26(1):229-42. Epub 2007 Jan 3.

Sinis N, Schaller HE, Schulte-Eversum C, Schlosshauer B, Doser M, Dietz K, Rosner H, Muller HW, Haerle M. [Tissue engineering of peripheral nerves] Handchir Mikrochir Plast Chir. 2006 Dec;38(6):378-89. German.

Schlosshauer B, Dreesmann L, Schaller HE, Sinis N. Synthetic nerve guide implants in humans: a comprehensive survey. Neurosurgery. 2006 Oct;59(4):740-7

Sinis N, Birbaumer N, Schwarz A, Gustin S, Unertl K, Schaller HE, Haerle M. [Memantine and Complex Regional Pain Syndrome (CRPS): effects of treatment and cortical reorganisation] Handchir Mikrochir Plast Chir. 2006 Jun;38(3):164-71.

Haber P, Sinis N, Haerle M, Schaller HE. Sonography of brachial plexus traction
injuries. AJR Am J Roentgenol. 2006 Jun;186(6):1787-91

Sinis N, Rennekampff HO, Haerle M, Schaller HE. Free flap monitoring with continuous
tissue oxygen tension measurement. European Journal of Plastic Surgery, Volume 28, Number 8 / April, 2006, p507-512

Sinis N, Schaller HE, Becker ST, Lanaras T, Schulte-Eversum C, Müller HW,
Vonthein R, Rösner H, Haerle M. Cross-chest median nerve transfer with the ulnar nerve: A new transplantation model in rats. Chirurgisches Forum 2006, Band 35, Springer Verlag, S. 377-79.

Sinis N, Schaller HE, Becker ST, Lanaras T, Schulte-Eversum C, Müller HW, Vonthein R, Rösner H, Haerle M. Haerle. Cross-chest median nerve transfer: A new model for the evaluation of nerve regeneration across a 40mm gap in the rat. J Neurosci Methods. 2006 Sep 30;156(1-2):166-72. Epub 2006 Apr 18.

Sinis N, Schaller HE, Schulte-Eversum C, Schlosshauer B, Doser M, Dietz K, Rösner H, Müller HW, Haerle M. Nerve regeneration across a 2 cm gap in the rat median nerve using a resorbable nerve conduit filled with Schwann cells.
J Neurosurg. 2005 Dec;103(6):1067-76.